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New species of superbug behind surge in serious human infections

by Sandhya Hirani
November 2, 2024
गंभीर मानव संक्रमणों में वृद्धि के पीछे नई प्रजाति का सुपरबग

New Delhi, November 2 (IANS). Recently a new type of bacteria has been found called Streptococcus dysgalactiae subspecies equisimilis (SDSE). According to a study, this bacteria is increasing the global rate of serious infectious diseases and is becoming resistant against many important antibiotics.

A person infected with SDSE is likely to develop infections of the skin, throat, gastrointestinal tract, and female genital tract, ranging in severity from strep throat (pharyngitis) to necrotizing fasciitis (flesh-eating disease). can happen till

“Although SDSE is closely related to group A Streptococcus (also known commonly as Streptococcus pyogenes), which has been very well researched,” said the team from the Houston Methodist Research Institute in the US. “Very little is known about SDSE.”

To better understand, the team used a complex method and studied 120 human samples of a specific strain, STG62647.

In a paper published in the journal mBio, the team explained that it is important to study the STG62647 SDSE variants because they have been shown to cause unusually severe infections.

The research team analyzed the genome of the subtype where information about its DNA is collected. They also decoded its transcriptome which provides a snapshot of the entire gene expression profile at the time the SDSE cells were collected. It also helped researchers understand the virulence of SDSE and the extent to which it can harm its host.

They found that based on mortality data, the potential for disease transmission was identified at an unexpectedly wide level (20-95 percent).

The results suggest that human genetics and underlying medical conditions contribute to the severity of the disease.

The team said the analysis revealed new data about the human bacterial pathogen, which could help in developing treatments and vaccine research. Along with this, the team has stressed the need for more research in this regard.

–IANS

MKS/AS

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