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Amazing Australian scientists developed real-time genome sequencing to fight deadly superbugs

by Sandhya Hirani
June 5, 2025
Amazing Australian scientists developed real-time genome sequencing to fight deadly superbugs

Sydney, 5 June (IANS). Australian scientists have achieved a great success in fighting Staphylococcus Aurus. Staphylococcus aureus is commonly known as the Golden Staff. It is a superbug, which causes more than a million deaths worldwide every year.

According to the report by the news agency Xinhua, the world’s first initiative has shown that real-time genome sequencing during serious infections helps doctors to identify resistant mutations quickly and make treatment personal.

Researchers at the Melbourne -based Peter Doharti Institute for Infection and Immunity (Doharti Institute) said that it would also help prevent the spread of antibiotic resistance.

Scientists at the Doharti Institute, working with seven local hospitals, said that traditionally bacteria are identified in hospitals only on the basis of species, which gives limited information about antibiotic resistance or genetic changes, but the genome sequencing gives the complete genetic profile of bacteria, which can affect the mutation which can affect the treatment.

Earlier bacterial development was usually studied years after treating patients, but this new method enables doctors to track the changes of bacteria into real-time and get immediate action. The study has been published in the Nature Communications Journal.

Stephano Giauliery, lead researcher at the Doharti Institute and Melbourne University, said that when the infection started and compared to the samples of golden staff when the infection failed, researchers found that mutations developed in bacteria in one-third of cases, leading to standard antibiotics to become ineffective.

Giauliery said, “In one case, the patient returned to the hospital two months after the closure of antibiotics after initially controlling the Golden Staff infection.”

He reported that resistance increased by 80 times in two months, but genomic information helped doctors to accommodate treatment and fix infection.

Researchers say that these findings are a major step towards the therapy targeted for bacterial infections and open the way for clinical trials in the future, which can make this approach standard exercises in hospitals around the world.

-IANS

FM/AS

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