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Depression during pregnancy also has connection with placenta: Research

by Sandhya Hirani
October 29, 2024
गर्भावस्था के दौरान डिप्रेशन का प्लेसेंटा से भी कनेक्शन: शोध

New Delhi, October 29 (IANS). A team of Australian researchers has found in their research that the placenta also has an unexpected effect on maternal mental health. This new discovery may help in understanding the cause of anxiety and depression during pregnancy.

Scientists at the Mater Research Institute at the University of Queensland have identified 13 different glucocorticoid receptor isoforms in the placenta, with one particular type being associated with anxiety and depression during pregnancy.

“Our research found that there are 13 different isoforms of the glucocorticoid receptor in the placenta, one isoform of which causes stress, anxiety and depression during pregnancy,” said Professor Vicki Clifton in a Genomic Press interview published in Brain Medicine. . “It activates an inflammatory response in the placenta in the presence of high cortisol levels.”

The research challenges conventional understanding of stress responses during pregnancy. While most glucocorticoid receptors work to suppress inflammation, this new variant works to increase inflammation. This shows the connection between stress and inflammation in pregnant women.

Professor Clifton’s research has also revealed important differences between male and female fetuses.

He said that currently we do not consider the sex of the fetus in obstetrics. I would like to see gender-specific care for premature newborns and pregnancy complications.

Research shows that the mother’s body may work differently depending on the sex of the fetus. This research creates new possibilities regarding pregnant care.

Now the team aims to find out how placental inflammation can affect the mental state of the mother. Due to which symptoms of anxiety and depression can increase during pregnancy. These findings could revolutionize the approach to perinatal mental health care.

–IANS

MKS/KR

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