New Delhi, 23 May (IANS). American scientists have prepared a new gene therapy, which can be sprayed through the nose and transported to the lungs and windpipe.
Gene therapy is effective only when the essential things related to treatment reach the right parts of the body. In gene therapy, it is necessary to take the treatment molecules to the right place of the body so that they can work properly. For this, Adeno-Associated Virus (AAV) genes therapy is used.
To further improve this technique, scientists from Mess General Brigham have designed a new form of AAV, named AAV.CPP.16. It can be given as spray in the nose.
In the initial research conducted on animals, this new technology proved to be more effective than the old AAV6 and AAV9. This better target the lungs and the windpipe and it can prove to be effective in treating respiratory and lung diseases.
Fengfeng Bei of the Department of Neuro Surgery, Brigham and Women Hospital, said that AAV.CPPPPPP.16 was earlier built to reach the central nervous system, but it is also working well in lung cells. Because of this, we also tested it to deliver medicines to the lungs through the nose.
In this research, AAV.CPP.16 gave better results not only in cell tests, but also in experiments conducted on mice and other animals.
He also used this method in giving gene therapy for viral infections. In this, the test on mice infected with Kovid-19 helped prevent the SARS-COV-2 virus from growing.
Scientists say more research is needed right now, but the results so far show that AAV.CPP.16 can be an effective way to provide direct treatment to the windpipe and lungs.
-IANS
AS/
