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Scientists discovered the cellular cause behind the increase in abdominal fat with age

by Sandhya Hirani
April 27, 2025
Scientists discovered the cellular cause behind the increase in abdominal fat with age

New York, 27 April (IANS). A team of American researchers have detected the cause of age-related abdominal fat, which helps to understand why our back becomes wide by reaching the middle of age.

This research has been published in the science journal, and its findings are expecting that new treatment methods may develop to prevent stomach fat and increase a healthy lifetime in future.

This research has been done by ‘City of Hope’. Arthur Rigs Diabetes and Metabolism Research Institute of the City of Hope At the Molecular and Cellular Endocrinology Associate Professor Kiong (Anabel) Wang, said, “People lose muscles with aging and increase the fat in the body, whether they live the same.”

He added, “We found that a new type of adult stem cells come into the body with aging and accelerate the production of new fat cells around the stomach.”

Wang and his team, along with UCLA lab co-author Shia Yang, experimented on mice, which were later confirmed on human cells.

Researchers focused on the White Edipose Tissue (WAT), which is the fat tissue responsible for age -related weight gain. Although it is known that fat cells get large with age, researchers suspected that WAT also produced new fat cells, which means that there could be no limit to its growth.

To test their estimate, researchers focus on adipocyte projector cells (APCS), which are a type of stem cells found in WAT, which turn into fat cells. The team first took APCS from young and old mice and transplanted them to young mice of other groups. The APCS extracted from old mice created a lot of new fat cells.

When the team transplanted APCS from young mice into old mice, these stem cells did not create much new fat cells. These results prove that the old APCS itself has the ability to create new fat cells. This conclusion shows that it is very important to control the construction of new fat cells to deal with age -related obesity.

-IANS

AS/

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