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Severity of Parkinson’s disease may increase bacteria of the mouth and intestine: study

by Sandhya Hirani
June 10, 2025
मुंह और आंत के बैक्टीरिया बढ़ा सकते हैं पार्किंसंस रोग की गंभीरता : अध्ययन

New Delhi, 10 June (IANS). A new study has shown that bacteria present in the mouth and intestine can make the problem of memory and low-understanding ability in Parkinson’s disease.

This research was conducted by scientists at King’s College London, who found that changes in intestine bacteria may further spoil the symptoms of the disease.

It is very difficult to identify Parkinson’s currently in its early stages, these changes in microbiome can serve as the initial signs of the disease, which can help doctors to detect and treat it in time.

Dr. Saeed Shoa, researcher at Kings College, said, “Bacteria of the mouth and intestine affect brain -related diseases. The imbalance in these can affect inflammation and immune system, which damages the brain.”

The study published in the journal ‘Gut Microbes’ analyzed saliva and stool samples of 228 people. There were two groups of Parkinson’s patients. One saw light cognitive problems and the other had dementia problems. They were compared to healthy people. The results found that people who had cognitive problems had more harmful bacteria in the intestine, which probably reached the intestine from the mouth.

This is called ‘oral-ghat translocation’, where the bacteria of the mouth go into the intestine and produce inflammation and toxins, which can damage the brain.

Research colleague Dr. Frederick Klassen said, “We do not know whether these bacteria are causes of cognitive decline or grows due to illness, but they deepen the symptoms.”

With the help of artificial intelligence, these bacteria and their toxins were identified, which can help for future treatment.

-IANS

MT/AS

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