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Stress can be more harmful in colon cancer: Research

by Sandhya Hirani
October 13, 2024
बड़ी आंत के कैंसर में और नुकसानदेह हो सकता है तनाव : शोध

New Delhi, October 13 (IANS). However, stress can cause many types of health problems. But it can cause more harm in colorectal cancer i.e. cancer of the large intestine. This has come to light in a research.

A team of Chinese researchers showed that chronic stress disrupts the balance of gut microbiota, which then accelerates the development of colon cancer.

Scientists have discovered in research that some bad bacteria can cause some stress-related diseases. Along with this, researchers identified a special type of bacteria, which can be treated.

The team from West China Hospital of Sichuan University in China used a cocktail antibiotic of vancomycin, ampicillin, neomycin and metronidazole to destroy the intestinal microbiota. Fecal microbiota were then transplanted to determine whether gut microbiota are essential for the role of stress in accelerating colon cancer progression.

The results showed that chronic stress not only caused tumors to rapidly increase in size, but it also reduced beneficial gut bacteria – particularly the Lactobacillus genus.

“Stress-related colon cancer progression may be attributed to a reduction in beneficial gut bacteria, as this weakens the body’s immune response against cancer,” said lead researcher Dr. King Li of the university. ”

“Through stool analysis, we found that Lactobacillus plantarum specifically regulates bile acid metabolism and improves the function of ‘CD8+ T’ cells. This shows how Lactobacillus can fight tumors,” Li said. Can increase immunity against.

Research has shown that Lactobacillus based therapies have great potential in treating patients, especially those affected by chronic stress.

“Restoring beneficial bacteria such as Lactobacillus in the gut may strengthen the body’s natural defenses against colon cancer,” Lee added.

The study was presented at the United European Gastroenterology Week 2024 in Vienna, Austria.

–IANS

MKS/AKJ

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