New Delhi, 21 February (IANS). Gut microbiom (microbes present in the intestine) play an important role in increasing the disease called multiple sclerosis (MS). It is an autoimmune disease that affects our central nervous system. A study has revealed this, which can help to understand why some people get this disease.
Our intestine consists of trillions of bacteria and other micro -organisms, including microbiome. These organisms live in our digestive system and affect our health.
Researchers at Yale University, USA, found that the amount of certain types of bacteria in the intestine of MS patients is different from common people. Also, the number of antibodies called “immunoglobulin A (IGA)” was also found to be low in these patients.
According to the research, the chief scientist, Associate Professor Erin Longbreak, “When MS patients have low bacteria covered with IGA, it shows that the balance between their body and intestine has deteriorated. It is possible that due to environmental reasons There is a change in the bacteria of the intestine, which increases the chances of MS. “
The study has been published in the magazine “Neurology Neuroeimunology and Neuroinflamation”. It included 43 people who had recently been MS and have not started any treatment yet. They were compared to 42 healthy people.
Examination of their stool samples revealed that patients with MS (multiple sclerosis) had less bacteria called ‘fecalibacterium’, while without treatment MS patients had more bacteria called ‘Monoglobus’.
Of these 43 patients, 19 were given treatment called “B-cell deployment therapy”, destroying the cells of the body’s immune system (immune system) that increase autoimmune diseases. Six months after treatment, when their stool samples were taken again, their gut microbiomes became like healthy people.
Professor Longbreak said that this study helps to understand how this drug works in the treatment of MS. Through this, it can also be known why some people have MS, while others are safe from it.
-IANS
AS/
