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Weight loss- If your weight is continuously decreasing without any effort, then do not take it lightly. Sometimes it is also due to some dangerous disease. If you do not feel any improvement even after eating healthy food, then definitely get a checkup done. Not only this, bone cancer affects mobility, especially when it is in the bones of the legs, spine, thighs. Sometimes it becomes difficult to walk in it. This happens due to pain and weakness in the affected bones. Overall health is affected.