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Time may take time to identify diabetes in men due to hidden genetic risk: Study

by Vaidehi Verma
September 30, 2025
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New Delhi, 30 September (IANS). According to a study, a common gene variant can delay diagnosis of type 2 diabetes in millions of men worldwide and can increase the risk of serious complications.

G6 PD deficiency is a genetic condition that affects over 40 million people worldwide, and especially found in people with African, Asian, Middle Eastern and Mediterranean backgrounds.

It is more common in men and is usually not detected because it rarely produces symptoms. However, the World Health Organization (WHO) appeals regular check -up for G6 PD deficiency in the population where it is common, but in many other countries it is not widely implemented.

Researchers at the University of Exeter found in collaboration with Queen Mary University of London (QMUL) that in men with G6 PD deficiency, type 2 diabetes is diagnosed after four years on an average after men without gene variants. Despite this, the condition has been diagnosed in less than one in 50 people.

This study published in the magazine diabetes care has shown that men with G6 PD deficiency are 37 percent higher than the problems of small blood vessels related to diabetes, such as eye, kidneys, and nerve damage, developing 37 percent than other diabetic patients.

Lack of G6 PD does not cause diabetes (diabetes), but it disturbs a common blood test, called HBA1C. This investigation is used for identification and monitoring of diabetes. Due to lack of G6 PD, the result of the HBA1C probe is incorrectly low.

Since this can cause doctors and patients to be confused, resulting in delay in diagnosis and treatment of diabetes, the team emphasized the need to develop new diagnosis methods, so that it is not too late to prevent serious complications.

Professor Ines Beroso of Exeter University said, “Our findings highlight the immediate need for changes in testing practices to deal with health inequalities. Doctors and health policy makers should keep in mind that HBA1C testing may not be accurate for people with G6 PDs and regular G6 PD testing can help identify people with risks. Important. “

HBA1C blood test is an international standard for managing type 2 diabetes and is used to diagnose diabetes in 136 countries around the world.

However, for people with G6 PD deficiency, this test may lower their blood sugar levels, which can significantly delay therapy and increase the risk of serious complications.

– IANS

Kanak/AS

Tags: Health/MedicineIANSScience Technology

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