Obesity is a problem affecting every second human being today and is gradually becoming a major concern. From children to elders, everyone is troubled by obesity, which is harming their body and overall health. For this reason, people are resorting to exercise and dieting in the gym to control their weight. Weight loss supplements, fat loss pills, powders and injections are also available in the market, and people are using them in large quantities due to the desire to lose weight quickly and lack of time. Recently, weight loss medicines like Monjaro and Vegovy have been officially launched in India. Ozempic is also quite popular in foreign countries. A recent study has shown that as soon as someone stops taking these weight loss injections, their weight starts increasing again.
Rebound effect of anti-obesity drugs
Drugs like semaglutide (Ozempic) and liraglutide are being seen as game-changers in the fight against obesity. Researchers Han Wu et al., from the Department of Endocrinology and Metabolism of Peking University People’s Hospital in China. Has claimed rebound effect in his research.
Researchers Han Wu et al. conducted a clinical trial of 1573 people in which they were given weight loss medications such as GLP-1 receptor agonists (such as semaglutide, liraglutide), orlistat, naltrexone-bupropion, and phentermine-topiramate for at least 4 weeks, and were monitored for 4 or more weeks after stopping the medications.
Research has shown that weight starts increasing again after about 8 weeks of stopping these medicines. According to research, when drugs like Ozempic and Vegovy are stopped, weight gain resumes after 8 weeks and continues for about 20 weeks. However, after 26 weeks, the weight stabilizes again.
After 8 weeks of stopping the weight loss medication, their weight increased by 1.5 kg, after 12 weeks by 1.8 kg and after 20 weeks without the medication, their weight increased by 2.5 kg. After six months, his weight stabilized, reaching a plateau. Reaching a plateau means that the rate of results slows down or stops.
The results were the same every time. Regarding this, Dr. Nandita, Consultant Diabetes Specialist, Chennai says that this is an interesting research, but similar results have emerged in other trials also. Even if you stop or stop taking the medication, weight gain will occur, even if you make lifestyle changes.
Weight loss occurs rapidly after taking the medicine and then increases again after stopping it. However, it increases only up to a certain level. This research does not say that weight loss drugs do not work. But as long as you use them, they work great. It is worth noting that recent research has also revealed that our cells have a memory which tries to keep the weight stable. This is why after rapid weight loss, as soon as the medicine is stopped, the weight increases to a certain level.
How to lose weight naturally?
You can lose weight even without injections and weight loss drugs. For this you will have to make some changes in your lifestyle. Increase your physical activity, from morning walks to daily exercise. Also, start using stairs instead of lift.
You should not starve yourself to lose weight. Instead, you should follow a healthy diet. Eat as many green vegetables and fruits as possible. Also, stay away from fast food. To lose weight, it is also very important to take 7 to 8 hours of sleep. Lack of sleep also leads to weight gain, and stress also contributes to weight gain. Therefore, we should include a right diet and lifestyle in our routine.
