Most people ignore itching in hands and feet, considering it as dry skin, allergy or minor irritation. But, if itching persists for no apparent reason, and there are no skin rashes, it may be a sign of a deeper internal problem. Doctors say that itching in the palms and soles can be an early sign of liver disease. When liver function decreases, bile acids accumulate in the body, which irritates skin nerves and causes intense itching. If this itching worsens at night, does not subside with moisturizers, or is accompanied by fatigue and jaundice-like symptoms, it is important to consult a doctor immediately.
Why do feet itch?
When the liver is not functioning properly, toxins and bile acids accumulate in the blood. These things affect the nerves of the skin, causing intense and persistent itching in the palms and soles of the feet. This type of itching is called “cholestatic pruritus” and can sometimes occur without a rash. This condition is often seen in several diseases, including primary biliary cholangitis, primary sclerosing cholangitis, and intrahepatic cholestasis during pregnancy. Why does itching occur in liver disease? Scientists find out these hidden causes. Scientists have not yet been able to identify any single cause of itching related to liver diseases. Experts believe that many different factors play a role in this.
accumulation of bile salts
When the liver is weak, bile salts in the body are not able to be filtered properly and start accumulating under the skin. This affects the nerves and can cause severe itching. However, it is also true that many people do not feel itching despite increased bile salt levels, while others experience itching even when levels are normal.
increased histamine
Increased levels of histamine are found in many patients suffering from liver-related itching. But the interesting thing is that antihistamines often do not provide relief.
role of serotonin
Serotonin can increase the feeling of itching in the brain. Some research suggests that it intensifies the itching sensation by affecting specific receptors in the nervous system. That is why it can sometimes be difficult to treat itching in liver disease.
Pregnancy or hormone therapy
Hormonal changes during pregnancy or hormone replacement therapy can increase itching. It has also been linked to changes in bile flow in the liver.
How to recognize itching related to liver?
According to a study published in the National Library of Medicine, itching that lasts for more than six weeks is considered chronic pruritus. There are some differences between common itching and itching caused by liver itching, such as:
itching without rash
It increases at night
It starts with the hands and feet
Ways to reduce itching
Don’t scratch your skin too much; This may cause infection.
If you have a habit of scratching at night, wear light gloves while sleeping.
Take bath with lukewarm or cold water, avoid hot water.
Use a room humidifier in cold weather.
